Linux, FreeBSD, MacOSX:

pear install http://pecl.php.net/get/xdebug

Add to php.ini:
zend_extension="/usr/local/php/modules/xdebug.so"


Windows:

Download Xdebug from http://xdebug.org

Add to php.ini:
zend_extension_ts="c:/usr/local/php/modules/xdebug.so"